Intermittent Hypoxia Exposure Can Prevent Reductions in Hemoglobin Concentration After Intense Exercise Training in Rats

Intense exercise training can induce low concentrations of hemoglobin, which may be followed by maladaptation. Therefore, it is important for athletes to prevent hemoglobin during intense training. In this study, we explored whether different protocols intermittent hypoxic exposure (IHE, normobaric hypoxia, 14.5% O 2 ) could the training-induced reduction in concentration rats. Six-week-old male Sprague-Dawley rats were subjected progressive treadmill over three weeks with IHE after exercise. lasted either 1 h, or h + (separated a 3-h interval) sessions. Hematological parameters, including [(Hb)], red blood cells (RBCs), and hematocrit (Hct), both renal serum erythropoietin (EPO) examined. We found that significantly reduced [Hb], RBCs, Hct, food intake body weight ( P < 0.01). Analysis reticulocyte content (CHr) counts suggested was not due iron deficiency other cofounding factors. The addition sessions alleviated Hct 0.05) without an obvious impact on > 0.05). Increase count from groups 0.05 0.01) suggests promotes erythropoiesis increase concentration. Furthermore, also increased EPO 0.05), although level statistically insignificant similarly effective at increasing preventing decreases Hct. Collectively, study used as new strategy reductions deserves future exploration athletes.